A 16-year-old patient is in the emergency room receiving nasal oxygen. She has a heart rate of 135/min, a respiratory rate of 40/min, and a peak expiratory flow (PEF) less than 50% of the predicted value. Wheezing and rales are audible without a stethoscope.
After successful treatment of the acute attack, the patient was referred to the outpatient clinic for follow-up treatment of her asthma. Successful strategies currently in use for asthma include all of the following EXCEPT (AIPG 2012)
|A||Avoidance of antigen exposure|
|B||Blockade of histamine receptors|
|C||Blockade of leukotriene receptors|
|D||Inhibition of phospholipase A 2|
|E||Inhibition of release of mediators from mast cells and leukocytes|
Histamine does not appear to play a significant role in asthma, and antihistaminic drugs, even in high doses, are of little or no value.