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Pharmacology

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Blood

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5 out of 45
 

A 23-year-old pregnancy woman is referred by her obstetrician for evaluation of anemia. She is in her fourth month of pregnancy and has no history of anemia; her grandfather had pernicious anemia. Her hemoglobin is 10 g/dL (normal, 12-16 g/dL).


If this patient has a young child at home and is taking iron-containing prenatal supplements, she should be warned that they are a common source of accidental poisoning in young children and advised to make a special effort to keep these pills out of her child's reach. Toxicity associated with acute iron poisoning usually includes (AIPG 2009)



A Dizziness, hypertension, and cerebral hemorrhage

B Hyperthermia, delirium, and coma

C Hypotension, cardiac arrhythmias, and seizures

D Necrotizing gastroenteritis, shock, and metabolic acidosis

E Severe hepatic injury, encephalitis, and coma

Ans. D Necrotizing gastroenteritis, shock, and metabolic acidosis

Acute iron poisoning often causes severe gastrointestinal damage resulting from direct corrosive effects, shock from fluid loss in the gastrointestinal tract, and metabolic acidosis from cellular dysfunction.

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