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Dermatology

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Collagen Vascular Diseases

Question
24 out of 54
 

"Pinch" purpura is diagnostic of - (AIIMS Nov 2014)



A Systemic primary amyloidosis

B Secondary systemic amyloidosis

C Idiopathic thrombocytopenic purpura

D Drug induced purpura

Ans. A
Systemic primary amyloidosis

a. In primary systemic amyloidosis amyloid deposition occurs in the wall of the blood vessels, this leads to an increase in skin fragility. As a result, petechiae and purpura develop in clinically normal skin as well as in lesional skin following minor trauma. Therefore the skin lesions in case of primary systemic amyloidosis are called pinch purpura. These lesions are pink in colour and translucent.

b. Common locations are

c. Face (especially the periorbital and perioral regions)

d. Flexural areas.

Collagen Vascular Diseases Flashcard List

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