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Biochemistry

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Lipid

Question
21 out of 26
 

Smoking cases all except: (AIIMS May 2009)

 

 
A Decrease HDL

 

B Decrease carboxy Hemoglobin & increase hematocrit

 

C Decrease mucus ciliary clearance

 

D Play a part in coronary artery disease

 

 

Ans. B Decrease carboxy Hemoglobin & increase hematocrit

Smoking increases the carboxy hemoglobin &can impair cilial transport

Smoking oxidizes this methionine to methionine sulfoxide and thus inactivates it. As a result, affected molecules of -antitrypsin no longer neutralize proteases. This is particularly devastating in patients (eg, PiZZ phenotype) who already have low levels of α-antitrypsin. The further diminution in α-antitrypsin brought about by smoking results in increased proteolytic destruction of lung tissue, accelerating the development of emphysema.


Diseases predisposed by smoking

Acute myeloid leukemia and cancers of the cervix, kidney, pancreas and stomach; abdominal aortic aneurysm, cataracts, periodontitis and pneumonia colorectal cancer, liver cancer, prostate cancer or erectile disfunction.

cancer of the bladder, esophagus, larynx, lung, mouth, throat. Smoking also has been linked to chronic lung disease, chronic heart and cardiovascular disease as well as reproductive problems.

Lipid Flashcard List

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