Loading....
Coupon Accepted Successfully!

Paediatric

Open Flashcards

Endocrinology

Question
3 out of 35
 

'Weak giants'are produced by - (AIIMS Nov 2014)



A Thyroid adenomas

B Thyroid carcinomas

C Parathyroid adenomas

D Pituitary adenomas

Ans. D

Pituitary adenoma [Ref Harrison 16b/e p. 2090; Nelson lP/e p. 2303, 23041

o In children and adolescent growth hormone hypersecretion prior to epiphyseal long bone closure causes gigantism.

o The muscles often appear enlarged but the1, have decreased force generation.

o So, hyperpituitarism causes giants which have weak muscles and the most common cause of hyperpituitarism is pituitary adenoma.

o Myopathy of hyperpituitarism -

• Patients with hyperpituitarism hate mild proximal weakness with muscle atrophy.

• Myopathy is related to the degreed of acromegaly.

o Remember that all endocrinal disorders cause myopathy but none of them cause gigantism except hyperpituitarism.

Endocrinology Flashcard List

35 flashcards
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
13)
14)
15)
16)
17)
18)
19)
20)
21)
22)
23)
24)
25)
26)
27)
28)
29)
30)
31)
32)
33)
34)
35)