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Physiology

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Nerve Muscle Physiology

Question
2 out of 24
 

Which is true about presynaptic inhibition? (AIIMS NOV 2012)

 

 
A Occurs due to hyperpolarisation of presynaptic membrane
B Occurs due to inhibition of release of positive neurotransmitter from presynaptic terminal
C Produces action potential
D Occurs due to blockage of presynaptic receptor.
Ans. A Occurs due to hyperpolarisation of presynaptic membrane

Presynaptic inhibition occurs as follows :

a. The neuron ‘A’ releases an excitatory NT, to excite neuron ‘B’. But neuron ‘C’ ends pre-synaptically on ‘A’ to decrease the release of the excitatory NT.

b. Some of the salient Features of Pre-synaptic Inhibition are :

a. It is example of axoaxonic synapse b. It is stimulated by general anaesthetics

c. It is inhibited by picrotoxin d. It is mostly due to GABA

c. So it occurs due to hyperpolarisation of presynaptic membrane and results in inhibition of release of positive neurotransmitter from presynaptic terminal

 

Nerve Muscle Physiology Flashcard List

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