20 year old boy with right ankle involvement swollen with nodular painful swelling & fever & malaise diag is:
|B||Weber christen disease|
Erythema nodosum Ref: Harrison, 17th edition, Page 126
a. Erythema nodosum (EN) is an acute, nodular, erythematous eruption that usually is limited to the extensor aspects of the lower legs.
b. Chronic or recurrent erythema nodosum is rare but may occur. Erythema nodosum is presumed to be a hypersensitivity reaction and may occur in association with several systemic diseases or drug therapies, or it may be idiopathic.
c. The inflammatory reaction occurs in the panniculus.
a. The eruptive phase of erythema nodosum begins with flulike symptoms of fever and generalized aching. Arthralgia may occur and precedes the eruption or appears during the eruptive phase.
b. Most lesions in infection-induced erythema nodosum heal within 7 weeks, but active disease may last up to 18 weeks.
c. In contrast, 30% of idiopathic erythema nodosum cases may last more than 6 months. Febrile illness with dermatologic findings includes abrupt onset of illness with initial fever, followed by a painful rash within 1-2 days.