Loading....
Coupon Accepted Successfully!

Dermatology

Open Flashcards

STD

Question
3 out of 42
 

25 yrs old laborer 3 yrs back presented with penile ulcer which was not treated. Later he presented with neurological symptoms for which he got treated. Test to monitor response to treatment is- (AIIMS Nov 2013)


A VDRL
B FTA ABS
C TPI
D RPR

Ans. A
VDRL

1. The above said laborer is suffering from neuro syphilis. The best test to monitor response to treatment is VDRL which is a Cardiolipin (Non-treponemal) Tests

2. Venereal Diseases Research Laboratory (VDRL)is the best test for monitoring therapy in INDIA. A titer of > 1:8 is positive and A titre <1:8 is a False Positive VDRL.

3. The other tests for Follow up

4. VDRL, IgM-FTA-ABS, IgM-ELISA

Ref: Harrison, 17th edition page no 1045

Table 162-3 Recommended Follow-Up Evaluation after Therapy for Syphilis

Stage of Syphilis

Tests to Perform

When to Perform

Re-Treatment Considered If:

Primary or secondary

Quantitative RPR or VDRL

HIV-uninfected: 6 and 12 months

HIV-infected: 3, 6, 9, 12, and 24 months

1. Titer increases by fourfold or

2. Titer fails to decline by fourfold or test fails to become nonreactive by 6 months or

3. Clinical signs persist or recur

Latent or late

Quantitative RPR or VDRL

HIV-uninfected: 6, 12, and 24 months

HIV-infected: 6, 12, 18, and 24 months

1. Titer increases by fourfold or

2. Initial titer of ï1:32 fails to decline by fourfold by 6 months or

3. New clinical signs develop

Neurosyphilis (asymptomatic or

1. If CSF pleocytosis was documented initially, repeat CSF exam.

1. Every 6 months until CSF cell count is normal

2. Until normal

1. CSF cell count has not decreased at 6 months or

2. CSF is not normal after 2 years

symptomatic)

2. Monitor decline in CSF protein and CSF-VDRL. (Note: Rate of decline may be slow.)

3. Quantitative serum RPR or VDRL.

3. 6, 12, 18, and 24 months

STD Flashcard List

42 flashcards
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
13)
14)
15)
16)
17)
18)
19)
20)
21)
22)
23)
24)
25)
26)
27)
28)
29)
30)
31)
32)
33)
34)
35)
36)
37)
38)
39)
40)
41)
42)