4 years old male child had febrile seizures, best prophylaxis (DNB June 2011)
|A||Paracetamol 6 hourly|
|B||Paracetamol and diazepam|
a. Prophylactic anticonvulsants are not indicated in uncomplicated febrile seizures.
b. Only phenobarbitone and Valproate have demonstrated clinical efficacy in preventing febrile seizures.
c. Phenytoin and carbamazepine are ineffective.
d. Phenytoin can produce hypocalcemia and this could become a cause for refractory seizures. Correction of calcium levels can restore responsiveness to phenytoin. Rest of the drugs can cause hypercalcemia.