50 year old male with positive family history of prostate Ca has come to you for a screening test. The most sensitive screening test to pickup prostate Ca is”
|C||DRE + PSA|
|D||Endorectal coil MRI with T, W and T2 Wimberger.|
a. Prostate cancer screening is an attempt to find unsuspected cancers, and may lead to more specific follow-up tests such as a biopsy, with cell samples taken for closer study.
b. Prostate cancer screening options include the digital rectal exam and the prostate-specific antigen(PSA) blood test.
c. Prostate cancer is usually slow-growing and more common among older men. However, most cancers never grow enough to cause symptoms, and most men that have prostate cancer will never become aware of it in their lifetime. Controversy over usage
d. Screening for prostate cancer is controversial because of cost and uncertain long-term benefits to patient.
e. Testing may lead to overdiagnosis and additional, but often unnecessary, testing and treatment.
f. Follow-up tests can include painful biopsieswhich can result in excessive bleeding and infection.
Provenge is a new vaccine treatment for the Ca prostate. Recently approve by FDA of USA.