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Breast

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A 12 years old boy presents with fever, loss of weight and a node each on right side of neck and right axilla. There is no other lymphadenopathy or hepatosplenomegaly. The histopathology is Hodgkin's lymphoma of lymphocytic predominant. The clinical staging of this patient is: (Shift to LymphomA



A Stage IB
B Stage IIA

C Stage IIB
D Stage IIIB

Ans. C Stage IIB (REF. HARRISON INTERNAL MEDICINE CHP 105 PG 385 EDN 18TH)

The Ann Arbor Staging System for Hodgkin's Disease

Stage

Definition

I

Involvement of a single lymph node region or lymphoid structure (e.g., spleen, thymus, Waldeyer's ring)

II

Involvement of two or more lymph node regions on the same side of the diaphragm (the mediastinum is a single site; hilar lymph nodes should be considered "lateralized" and, when involved on both sides, constitute stage II diseasE.

III

Involvement of lymph node regions or lymphoid structures on both sides of the diaphragm

III1

Subdiaphragmatic involvement limited to spleen, splenic hilar nodes, celiac nodes, or portal nodes

III2

Subdiaphragmatic involvement includes paraaortic, iliac, or mesenteric nodes plus structures in III1

IV

Involvement of extranodal site(s) beyond that designated as "E" More than one extranodal deposit at any location Any involvement of liver or bone marrow

A

No symptoms

B

Unexplained weight loss of >10% of the body weight during the 6 months before staging investigation

Unexplained, persistent, or recurrent fever with temperatures >38°C during the previous month

Recurrent drenching night sweats during the previous month

E

Localized, solitary involvement of extralymphatic tissue, excluding liver and bone marrow

Breast Flashcard List

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