The Endocrine System
A 17 year old girl who was evaluated for short height was found to have an enlarged pituitary gland. Ho T. was low and TSH was increased. Which of the following is the most likely diagnosis? (AIIMS May 2012)
|B||TSH-secreting pituitary tumor|
|C||Thyroid target receptor insensitivity|
Analyzing all option,
• In pituitary adenoma/TSH secreting pituitary tumor increased TSH with increased T3/4 would be seen. (excludes ‘a’ and ‘b’)
• In thyroid hormone resistance increased T4 as well as T3, with low TSH will be seen. (option 'c' excluded)
• Primary hypothyroidism is due to defect in the thyroid gland itself. This is associated with high TSH with low T4, will be seen.