A 2 yrs old child comes with I year h/o of generalized edema. His B.P. is 107/70mm urine examination shows hyaline cast, proteinuria +++, WBC & RBC are nil. The Likely diagnosis is - (AIIMS Nov 2013)
|C||Focal segmental glonurulosclerosil|
|D||Low serum complements level|
a. It is a case of nephrotic syndrome due to mirimal change disease (MCD).
b. MCD is the most common cause of nepbrotic syndrome in children*
Microscopic findings of urine in MCD
i. Principally albumin (which is a low molecular vteight protein)
ii. High molecular weight Proteins are seen in minimal qmounts.
iii. This type ofproteitturia is known as selcctive pruteinuria-
hyaline cast - can be seen
b. Focal segmental Glomeruloclerosis can also cause nephrotic syndrome but the urine patients will reveal protein, WBCs and RBC s .