Gram Negative Spiral
A 21-year-old woman visits her obstetrician and is later diagnosed with secondary syphilis. On further questioning, it is determined she is allergic to penicillin. Because Treponema pallidum is known to cross the placenta, treatment is started immediately. Which antibiotic would be most appropriate in this situation?
a. Erythromycin and doxycycline are used when allergy to penicillin is present. Doxycycline is contraindicated in pregnant women because it crosses the placenta and is toxic to the fetus.
b. Ceftriaxone and tetracycline are not used for the treatment of syphilis. Penicillin is contraindicated because of the patient's allergies.