General Parasitology and Protozoa
A 24 year old primi in her 8th month of pregnancy develops a positive igm titer to T. Gondii for the first time. She should be advised by her physician that
|A||That this child and all future fetuses would be infected|
|B||That the new born with positive anti-toxoplasma igg response should be treated with anti-parasitics|
|C||That future infections can be avoided by proper vaccination and deworming of cats|
|D||That chorioretinitis can be prevented by drug treatment of an infant with positive igm response.|
a. Presence of igm in the primi in 8th month of pregnancy indicates recent primary infection.
b. Incidence and severity of congenital toxoplasmosis vary with the trimester during which the infection was acquired by the mother
c. Infection acquired in the first trimester by women who were not treated with anti–T. Gondii drugs results in congenital infection in 10% to 25% of cases.
d. For second- and third-trimester infections, the incidences of fetal infection ranged between 30% and 54% and 60% and 65%, respectively.
e. Majority of children born of women who acquire their infection during the third trimester as in this case are born with the subclinical form of the infection.
f. Signs or symptoms of congenital toxoplasmosis subsequently develop in most infants with subclinical infection at birth and can be prevented with appropriate treatment- Pyrimethamine with sulfadiazine.
If IgM to toxoplasma is positive in the neonate, then appropriate treatment will prevent the complication