A 29-year-old man complains of a rash on his chest. He has no other associated symptoms and there is no pain or pruritus. It has grown slowly over the past 4 months. He is monogamous in a homosexual relationship and has never been tested for HIV infection. He smokes tobacco occasionally. He takes no medications. On physical examination, he has no other lesions and no lymphadenopathy. Which of the following conditions do you expect this patient to have? (AIIMS Nov 2014)
|A||Hepatitis C infection|
|B||Human herpes virus 8 (HHV-8) infection|
|D||Staphylococcus aureus colonization|
|E||Subacute bacterial endocarditis|
Human herpes virus 8 (HHV-8) infection
1). The lesion shown is Kaposi’s sarcoma (KS).
2). The lesion is also commonly found on the extremities, face, and in the oral cavity.
3). It typically appears as painless purple/brown macules, plaques, and nodules. They may be confused with other pigmented lesions.
4). KS is the only sarcoma associated with a virus (HHV-8). The most common presentation is in patients infected with HIV, usually with advanced immunosuppression with CD4+ T cell counts <200/μL.
5). Folliculitis due to Staphylococcus aureus causes more pain and redness.
6). The cutaneous embolic or immunologic manifestations of bacterial endocarditis are smaller and typically found in the extremities.
7). Hepatitis C infection may cause skin lesions due to cryoglobulinemia; however, these appear as vasculitic lesions typically on the lower extremities.
8). There is no relation between hepatitis C infection and KS. Scabies infection will cause itchy papules and burrows.