Gram Positive Bacilli
A 4-month-old infant presents with failure to thrive, progressive muscular weakness, and poor head control. The mother states that she feeds the baby soy-based formula sweetened with honey. Organism most likely to be responsible is?
a. This is a history of Floppy baby syndrome (infant botulism) due to C. botulinum.
b. The food implicated is honey. Other clinical varieties of botulism are food botulism (due the consumption of canned food) and wound botulism (due to the local infection of the wound with C. botulinum).
c. The botulinum toxin is the most potent toxin causing disease in humans. It acts by blocking the release of acetylcholine from motor nerve endings at the neuromuscular junctions leading to descending flaccid paralysis.