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Dermatology

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Blistering Diseases

Question
22 out of 32
 

A 40-year-old man had multiple blisters over the trunk and extremities. Direct immunofluorescence studies showed linear IgG. Which of the following is the most likely diagnosis? (AIIMS Nov 2012)



A Pemphigus vulgaris
B Pemphigus foliaceus

C Bullous pemphigoid
D Dermatitis herpetiformis

Ans. C
Bullous pemphigoid

1). Bullous pemphigoid is a subepidermal blistering skin disorder generally seen in the old people.

2). Lesions typically consist of tense blisters on either normal appearing or erythematous skin.

3). The lesions are usually distributed over the lower abdomen, groin, and flexor surface of the extremities; oral mucosal lesions are found in 10 to 40% of patients.

4). Direct immunofluorescence microscopy of normal-appearing perilesional skin shows linear deposits of IgG and/or C3 in the basement membrane.

Blistering Diseases Flashcard List

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