Loading....
Coupon Accepted Successfully!

Medicine

Open Flashcards

Liver & GIT

Question
8 out of 23
 

A 41 year old male patient presented with recurrent episodes of bloody diarrhea & mucus for 5 years. Despite regular treatment with adequate doses of sulfasalazine, he has had several exacerbations of his disease and required several weeks of steroids for the control for flares. What should be the next line of treatment for him? (AIIMS Nov 07)



A Methotrexate
B Azathioprine

C Cyclosporine
D Cyclophosphamide

Ans. B Azathioprine

Treatment-

Mild Mod-Severe Fulminant Maintenance

(5-ASA)

(a) Sulfasalazine(3-6g/d) (a) 5-ASA I.V.Glucocorticoid 5-ASA

(b) Olsalazine (1-3 g/d ) (b) Glucocorticoids I.V.Cyclosporine 6-Mercaptopurine

( oral/ enema ) Azathioprine


Management of ulcerative colitis (Ref: Harrison 18th edition, chapter 295)

Indication of surgery:

1. Perforation

2. Massive hemorrhage

3. Toxic megacolon (diameter of transverse colon more than 6 cm in X-ray abdomen)

4. Failure to respond to medical therapy

Crohn’s disease- (Ref. H-18thedi, Pg 2483)

Definition- It is a recurrent, chronic disease process involving trans mural part of GIT anywhere from mouth to the anus.

Liver & GIT Flashcard List

23 flashcards
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
13)
14)
15)
16)
17)
18)
19)
20)
21)
22)
23)