A 48 year old woman was admitted with a history of weakness for two months. On examination, cervical lymph nodes were found enlarged and spleen was palpable 2 cm platelet count 2.37Lac/mm and total leukocyte count 40000 /mm, coarse clumped chromatin.
Bone marrow revealed a nodular lymphoid infiltrate. The peripheral blood lymphoid were positive for CD19, CD5, and CD 23 and were negative for CD 79 Band FMC –7. Most likely diagnosis? (AIIMS Nov. 2011)
|A||T-cell rich B - cell lymphoma with leukemic spill over in blood.|
|B||Chronic lymphocytic leukemia|
|C||Mantle cell lymphoma|
|D||A definite diagnosis can not be made in this patient without lymph node biopsy|