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Medicine

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Endocrine

Question
9 out of 33
 

A 50 yr old male with type 2 diabetes mellitus is found to have 24 hr urinary albumin of 250 mg. Which of the following drugs may be used to retard progression of renal disease: (AIIMS Nov 2009)



A Hydrochlorothiazide
B Enalapril

C Amiloride
D Aspirin

Ans. B

Enalapril

In diabetic patient ACEI not only control the BP but they also reduce the progression of nephropathy. Hence ACEI is the drug of choice in diabetes for control of BP as well as in reducing progression of nephropathy. In this case already albuminuria is there hence ACEI will reduce further progression of nephropathy.

Recent Advances: Telmisartan is the only ARB which acts on PPAR gamma receptor. So it is the ARB of choice that should be used in diabetes (This point is not given in 18th ed. of Hari also!!!).

Endocrine Flashcard List

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