A 7 Month child is hospitalized for a yeast infection that does not respond to therapy. Patient has a H/O multiple, acute pyogenic infections. O/E spleen & lymph nodes are not palpable. DLC shows N95L1M4. BM biopsy contains no plasma cells or lymphocytes. CXR reveals the absence of a thymic shadow. Tonsils are absent. His findings are most consistent with.
|B||Chronic granulomatous disease|
|C||Severe combined immunodeficiency|
This is a clinical history of both humoral (acute pyogenic infections) and cell-mediated immunodeficiency (yeast infection), which is seen in SCID (severe combined immunodeficiency).