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Paediatric

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Renal System

Question
51 out of 61
 

A 8 yr old boy presents with petechie, azotemic oligurea altered sensorium in casualty. There is history of diarrhoea for the past 5 days. The clinical diagnosis is - (AIPG 2011)



A Acute prophyria

B Idiopathic thrombocytopenic purpura

C H.S. purpura

D H.U.S.

Ans. A

Hemolytic uremic syndrome

o The boy is suffering from hemolytic uremic syndrome.

Hemolytic uremic syndrome

a. HUS is characterized by the trisd of -

i. Anemia (microangiopathic hemolytic anemia)

ii. Renal failure (microangiopathy of kidney involving glomerular capillaries and arteriales).

iii. Thrombocytopenia (due to platelet destruction)

b. HUS is common in children under 2 years of age. (But may also occur in older children).

c. It usually follows an episode of acute gastroenteritis.

d. The prodrome is usually of abdominal pain, diarrhoea and vomiting.

e. Shortly thereafter, signs and symptoms of acute hemolltic anemia, thrombocytopenia and acute renal failure ensue.

f. Sometimes neurological findings also occur (But usually absent and differentiate HUS from TTP).

Renal System Flashcard List

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