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Pathology

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Genetics

Question
7 out of 18
 

A couple with a family history of beta thalassemia major in a distant relative has come for counseling. The husband has HbA2 of 4.8% and the wife has HbA2 of 2.3%. The risk of having a child with beta thalassemia major is : (LQ)



A 50%
B 25%
C 5%
D 0%

Ans. D 0%

Normal % of HbA2 ranges from 1.5% to 3%. Husband has marginally elevated value for HbA2 so he is a thalassemia minor. So in the progeny no child will have thalassemia major

Genetics Flashcard List

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