A man takes peanut and develops, tongue swelling, neck swelling, stridor, hoarseness of voice. What is the probable diagnosis - (AIIMS Nov 2012)
|D||FB in larynx|
i.e., Angioneurotic edema
Hereditary Angioneurotic edema is a deficiency / nonfunctioning of C1 inhibitors, a condition characterized by episodic angioedema of the subcutaneous tissue or the mucosa of respirator &/or alimentary tracts elected by ingestion of fresh fruits, shellfish fish, milk products, chocolate, legumes including peanuts & drugs. Uncommonly it may occur secondary to inhalation or physical contact with pollens, animal dander and mold spores and emotional stress. The diagnosis is suggested not only by family history but also by lack pruritis and of urticarial lesions, the prominence of recurrent gastrointestinal attacks of colic and episodes of laryngeal edema (hoarseness of voice & stridor).
1. Associated with Food Allergy
3. Angioedema (Swelling involving Face, Lips, Tongue Eyelids)
4). Upper Respiratory obstruction
6). Vascular Collapse (Hypotension)
8 Family History
4). Present (due to swelling of larynx)
5). Not a prominent manifestation (often non pruiritiC.
6). Not a prominent manifestation (Presence of vascular collapse suggests systemic anaphylaxis)
8. Present in Hereditary Angioneurotic edema
5). Prominent manifestation
8. Often not present