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Medicine

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Hematology

Question
6 out of 16
 

A patient has Hb 6gm%, folic acid 8 ng/ml, vitamin B12 60pg/ml, serum iron 160μg/dl, and MCV-104. The diagnosis is: (AIIMS Nov 2009)



A Iron deficiency anemia
B Vitamin B12 deficiency

C Folic acid deficiency
D Pyridoxine deficiency

Ans. B

Vitamin B12 deficiency

Causes of Vitamin B12 Deficiency (Ref. Hari- 18th ed., Pg. 867, table 105.4)

1. Deficient diet (pure plant diet)

2. Malabsorption

3. Pernicious anemia (Intrinsic factor deficiency) , Partial/total gastrectomy, Crohn’s disease, Tropical sprue, Ileal resection, ileo cecal disease. (AIIMS Nov 09)

4. Blind loop syndrome (Bacterial overgrowth causes B12 deficiency)

5. Chronic pancreatitis

6. Fish tapeworm (Diphyllobothrium latum).

Vit B12

Folate

Source

Vegetable – Poor

Animal food – Rich

Vegetable – Rich

Animal food - Poor

Daily requirement

2-4 μg/day

100 μg /day

Main site of absorption

Ileum

Duodenum & jejunum

Body store

2-5 mg

5-20 mg

Body store exhaust in

App. 4 years

App 4 Month

Hematology Flashcard List

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