General Parasitology and Protozoa
A patient in the city of Pune was diagnosed with malaria acquired through a blood transfusion. A discussion of this case by physicians included the following statements. Which statement is correct?
|A||The infected blood contained sporozoites.|
|B||The patient should be treated with chloroquine and primaquine.|
|C||The patient should be treated to eradicate the stages responsible for symptoms.|
|D||The blood donor had chloroquine-resistant malaria.|
a. The primary goal should be to treat the patient to eliminate the erythrocytic cycle that is the cause of symptoms.
b. This would constitute a radical cure because the liver phase only occurs if infection is initiated by sporozoites. Thus, treating with primaquine (B) is not necessary because the patient will not harbor hypnozoites.
c. Likewise, (A) is not correct because sporozoites are only acquired from mosquitoes. Transfusion malaria is caused by schizonts and merozoites present in the transferred blood.
d. There is no way to know that the malaria is chloroquine resistant until after treatment with chloroquine (D)