A patient is on aspirin, what will be the finding? (AIPG 2010)
Effects of aspirin Therapy
1. Ingestion of aspirin significantly prolongs the BT
2. Aspirin irreversibly inhibits COX –1 and COX – 2. COX inhibition leads to prevention of TXA2 synthesis and impairment of platelet secretion and aggregation.
3. The effect of aspirin on platelet function occur within 1 hours and lasts for the duration of the affected platelet’s life span i.e. 1 weeks.