General Virology and DNA Viruses
A patient presents to a physician because of pain during defecation accompanied by blood in the stool. Examination demonstrates a large perianal mass. Biopsy of the rectal mass following resection demonstrates a condyloma in which transformation to frank carcinoma has occurred. Which virus would most likely be associated with these lesions? (AIPG 2012)
a. This is the history of anal wart, which has complicated to carcinoma. This condition is seen in male homosexuals. The cause in human papilloma virus.
b. HPV is a nonenveloped, dsDNA-containing virus. It has icosahedral symmetry and belongs to papovaviridae. It is a noncultivable virus. Types 16 and 18 are high-risk types responsible for cervical cancer.