A patients is given tacrolimus, which antibiotic should not be given to him? (AI 2009)
· Rifampicin is a potent enzyme inducer. The drug has the chance of inducing the metabolism. This might reduce the efficacy of tacrolimus and graft rejection may occur.
· Gentamicin, cisplatin and vancomycin have additive nephrotoxic effect with tacrolimus, but dose reduction may protect from these adverse effects.