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Orthopaedic

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Arthritis

Question
77 out of 101
 

A woman developed acute pain in the right knee. Synovial fluid aspiration showed CPPD crystals. Which of the following tests should be done further for evaluation? (AIPG 2012)



A ANA
B RF

C TSH
D CPK

Ans. C

TSH

a. Pseudogout is characterized by the inflammation of the joints and can lead to arthritis.

b. The deposition of calcium pyrophosphate dihydrate crystals in and around the joints causes the inflammation and results into pseudogout.

c. Pseudogout and gout coexist with each other, wherein, both types of crystals are present in the joint fluid.

d. Pseudogout affects men and women equally and is seen to commonly affect the older people.

Causes:

Conditions Associated with Calcium Pyrophosphate Dihydrate Disease

1. Aging

2. Disease-associated

a. Hypothyroidism(commonest)

b. Primary hyperparathyroidism

c. Hemochromatosis (AIPG 2006)

d. Hypophosphatasia

e. Hypomagnesemia

f. Chronic gout

3. Post meniscectomy

4. Hereditary

Symptoms of Pseudogout

a. The symptoms - painful joint inflammation, mostly in knees (most common joint involve), wrists, hips and other major joints, while others may exhibit stiffness and lingering chronic pain in the arms and legs.

b. Pseudogout generally starts off in one joint and then gradually inflammation occurs in multiple joints.

c. Pseudogout affects the larger joints (knees, shoulder, wrists and hip). The joints affected by pseudogout are the ones with calcified articular cartilage (chondrocalcinosis).

Treatment of Pseudogout

a. Ice packs are applied to reduce the pain and inflammation.

b. High doses of colchicine for inhibiting the migration of granulocytes.

c. NSAID.

d. Aspiration of synovial fluid in the affected joints is another treatment option that is seen to shorten the attack duration.

e. To relieve the joints of acute inflammation, corticosteroids are sometimes injected directly.

Arthritis Flashcard List

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