CNS Part- 2
A young male patient recently diagnosed as schizophrenic develops severe muscle cramps with torti collis a short time after drug therapy is initiated with haloperidol. The best course of action would be to: (AIPG 2009)
|A||Add clozapine to the drug regimen|
|B||Discontinue haloperidol and observe the patient|
|C||Give oral diphenhydramine|
|D||Switch the patient to fluphenazine|
a. Acute dystonic reactions are usually very painful and should be treated immediately with parenteral administration of a drug that blocks muscarinic receptors.
b. Adding clozapine will not be protective, and fluphenazine is as likely as haloperidol to cause acute dystonia.
c. Oral administration of diphenhydramine is a possibility, but the patient may find it difficult to swallow and it would take a longer time to act.