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Medicine

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Respiratory

Question
1 out of 7
 

ABPA results in which type of hypersensitivity reacting? (LQ)



A I
B III

C Both A & B
D IV

Ans. C

Both A & B

Aspergillus This group of fungi affects the lung in 5 ways:


1). Asthma:

2). Aspergilloma

3). Invasive aspergillosis

4). Extrinsic allergic alveolitis

ABPA

1). This results from a Type I and III Q hypersensitivity reaction to Aspergillus fumigatus.

2). Early on, the allergic response causes bronchoconstriction, but as the inflammation persists, permanent damage occurs, causing proximal bronchiectasis Q

3). Symptoms: wheeze, cough, sputum (plugs of mucus containing fungal hyphae), dyspnoea and recurrent pneumonia Q.