ATRA is useful in the treatment of which of the following type of AML? (LQ)
|D||Erythro leukemic leukemia|
Treatment of promyelocytic leukemia is by tretinoin.
a. It is an oral drug that induces the differentiation of leukemia cells bearing the t (15 .17)
b. It is not effective in other forms of AML.
c. APL is responsive to cytarabine and daunorubicin but about 10% of patients treated with these drugs die from DIC induced by the release of granule components by dying tumor cells.