General Virology and DNA Viruses
About interferon true is:
|A||It is a synthetic antiviral agent|
|B||Prevents entry of the virus into the cell|
|C||Is specific for a particular virus .|
|D||Renders cells refractory to viral infection|
a. Interferons are glycoproteins produced in response to viral infection.
b. They make the uninfected host cell refractory to viral infection by inhibiting the protein synthesis by destroying viral mRNA. The interferon induce by one virus can confer protection against infection by the same or unrelated virus.
c. RNA viruses are better induces of interferon than DNA viruses. Viruses vary in their susceptibility to interferon.
d. Based on antigenic characters, cell of origin and other properties, they are classified into three types – alpha, beta, gamma. Alpha is produced by leukocyte. Beta is produced by fibroblast and gamma is produced by T lymphocyte.