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Pathology

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Inflammation

Question
12 out of 13
 

Acute phase reactants of inflammation are - (LQ)



A Haptoglobin
B C-reactive protein (CRP)

C Transferrin
D Prostaglandins

E Fibrinogen

Ans. A Haptoglobin; 'b' i.e., C-reactive protein (CRP); 'c' i.e., Transferrin; 'e' i.e., Fibrinogen

Acute phase proteins (reactants)

Acute phase reactants are a class of proteins whose plasma concentration increases or decreases in response to inflammation.

This response is called the acute phase reaction (acute phase response)

It should be noted that acute phase proteins not only increase in response to inflammation; some decrease also

1. Proteins which increase in response to inflammation Positive acute phase proteins

2. Proteins which decrease in response to inflammation Negative acute phase proteins

a. Positive acute phase proteins

i. C-reactive protein (β1-globulin) ii. α-1 antitrypsin iii. Fibrinogen, prothrombin, vWF

iv. Ferritin v. Serum amyloid A vi. Plasminogen, Factor VIII

vii. α-2 microglobulin viii. Mannose binding protein ix. D-dimer protein

x. Haptoglobulin xi. Ceruloplasmin xii. Complement factors

b. Negative acute phase proteins

i. Albumin & Prealbumin ii. Transferrin iii. Transthyretin

iv. Transcortin v. Retinol binding protein

Inflammation Flashcard List

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