Biomedical Waste Management, Disaster Management, Occupational Health, Genetics and Health, Mental Health
All are features of Silico-tuberculosis except:
|A||High sputum AFB +ve|
|B||Children of such cases do not get disease|
|C||Impairment of total lung|
1. Patients with silicosis are particularly susceptible to tuberculosis (TB) infection, known as 'Silicotuberculosis' (ST)
i. The reason for the increased risk, 10-30 fold increased incidence, is not well understood
ii. It is thought that silica damages pulmonary macrophages, inhibiting their ability to kill mycobacteria
2. In recent years doubts have risen in the association between silicois and tuberculosis as:
i. Sputum is rarely AFB+
ii. Children and women of STs do not develop tuberculosis
- Post mortem of STs fail to prove existence of tuberculosis
- Radiological evidence of both conditions is similar.
1. Among the occupational diseases, silicosis is the major cause of permanent disability and mortality
2. Particles of the size 0.5 - 3 microns are most dangerous for causation of silicosis
3. IP: Few months to 6 years
4. X-ray shows 'snow storm appearance'
5. No effective treatment is available
6. Silicosis is a notifiable disease under Factories Act, 1948 and Mines Act 1952.