All are true about nitrous oxide except':
|B||Bone marrow depression|
|D||Safe in middle ear surgery|
Safe in middle ear surgery
a. Ingress of nitrous oxide can significantly increase the middle ear pressure and can displace the graft after tympanoplasties. So nitrous oxide should be avoided in middle ear surgery.
b. N2O inactivates cyanocobalamin' so can cause megaloblastic anemia. Its teratogenicity is only proven in animals,