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Pathology

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Genetics

Question
3 out of 7
 

All are true about Fragile X syndrome except: (LQ)



A Is due to triple nucleotide repeat mutation at Xq27.3

B CGG repeats located FMR 1 gene.

C CGG expansions occur during oogenesis

D The expansions affect the coding region i.e. exons

E Is 2nd most common genetic cause of mental retardation, after Down syndrome

Ans. D The expansions affect the coding region i.e. exons

In Fragile X Syndrome, CGG repeats affect the non- coding regions