22 out of 71
All are true about levamisole EXCEPT (LQ)
|A||Act as an immunostimulator|
|B||Act as an immunodepressor in high doses|
|C||Single dose is sufficient for the treatment of psoriasis|
|D||Acts as antihelminthic by causing depolarization|
Ans. C Single dose is sufficient for the treatment of psoriasis (Ref. : Goodman & Gilman 11th/1422)
- Levamisole is an immunomodulator acting as immunostimulant at low doses and immunodepressant at high doses.
- It was used as anti-helminthic and causes depolarization by stimulating nicotinic receptors.
- It is used for treatment of colorectal carcinoma in combination with 5-FU.
- It is slow to act in psoriasis and requires two-day therapy per week for prolonged periods.