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Pathology

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The Lungs

Question
38 out of 54
 

All are true about phagocytosis except (LQ)



A Size of the particle ingested is less than 0.5 micrometer

B Size of the particle ingested is more than 0.5 micrometer

C Combines with lysosome forming phagolysosome

D Amoeba and other unicellular organisms make their living out of it

Ans. A 1-5 micron

In pneumoconiosis, the most dangerous particles range from 1-5 micron in diameter, because they may reach the small airways and air sacs and settle in their linings.

Note-:

The solubility and cytotoxicity of particles modify the nature of pulmonary response.

ln general, the smaller the particle, the higher the surface area-to-mass ratio, and the more likely and more rapidly toxic levels {l appear in the pulmonary fluids.

Larger particles resist dissolution and so may persist within lung parenchyma for years.

Larger particles tend to evoke fibrosing collagenous pneumoconiosis, such as characteristic of silicosis.

The Lungs Flashcard List

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