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Pathology

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Neoplasia

Question
14 out of 24
 

All are true for molecular basis of cancer except: (LQ)



A Non- lethal genetic damage lies at the heart of carcinogenesis

B mi – RNA’s a new class of regulatory molecules acts as either oncogenes/tumor suppressor genes

C Tumors are polyclonal

D Four classes of normal regulatory genes exist

Ans. C Tumors are polyclonal

A tumor is formed by the clonal expansion of a single precursor cell that has incurred the genetic damage (i.e. tumors are monoclonal). Four classes of normal regulatory genes—the protooncogenes, tumor suppressor genes, genes that regulate programmed cell death (apoptosis), and genes involved in DNA repair—are the principal targets of genetic damage

Neoplasia Flashcard List

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