All are used in the treatment of hot flushes except
a. For women with moderate to severe vasomotor symptoms, estrogen or estrogen/progestin regimens are the most
b. Effective approach to symptom relief.
c. Alternatives to hormone therapy for vasomotor symptoms include SSRIs such as paroxetine or venlafaxine orally.
d. Gabapentin, an antiseizure medication, is also effective orally. Clonidine given orally or transdermally, may also
e. Reduce the frequency of hot flushes, but its use is limited by side effects, including dry mouth, drowsiness and hypotension.