All have Malignant risk except:
|C||Peutz Jager syndrome|
Polyps: Polyp is a grossly visible profusion from mucosal surface and its classified pathologically is:
a. Juvenile polyp
b. Hyperplastic polyp
c. Adenomatous polyp
i. Adenomatous polyps have special clinical significance because only adenomatous polyps are clearly premalignant. Juvenile polyp and hyperplastic polyp are non neoplastic epithelial tumors of intestine. There is no increased risk of malignancy.
ii. Hamartomatous polyps or juvenile polyps are characterized by overgrowth of normal component of colon, such as epithelium and connective tissue.
iii. These hamartomatous polyps are seen in following syndromes - familial juvenile polyposis, Cronkhite - Canada and Peutz-Jeghers syndrome unlike solitary juvenile polyps (hamartomatous polyps), polyps associated with familial polyposis and Peutz Jeghers syndrome may degenerate into adenomas and eventually into carcinoma.
iv. There is increased risk of gastrointestinal as well as extra gastrointestinal malignancies.