All of the following are used in the treatment of eclampsia except (DNB June 2013)
|A||Lytic cocktail regime|
a. Magnesium sulphate is the drug of choice of eclampsia. It reduces motor endplate sensitivity to acetylcholine and thereby reduces neuromuscular irritability. It has no detrimental effect on the neonate within therapeutic limits.
b. Menon first applied lytic cocktail regime in India in 1961. It consists of chlorpromazine, Phenergan ® and pethidine.
c. Phenytoin is also used to control convulsions and it is given by slow IV route with ECG monitoring. Initial dose is 10 mg/kg followed by 5 mg/kg 2 hours later. Thereafter 200 mg is given orally 12 hourly.
d. Diazepam is used in initial doses of 40 mg intravenously.