All of the following can cause megakaryocytic thrombocytopenia, except- (AIIMS Nov 2010)
|A||Idiopathic thrombocytopenic purpura|
|B||Systemic lupus erythematosus|
|D||Disseminated intravascular coagulation (DIC)|
Aplastic anemia will have …
1. Amegakaryocytic thrombocytopenia IS due to Bone marrow defect so no megakaryocyte is produced ..e.g. Aplastic anemia/Myelofibrosis/ chemo therapy/radiotherapy…
2. Megakaryocytic thrombocytopenia –is due to platelet destruction in peripheral blood and so bone marrow will form megakaryocytes in excess…e.g. DIC /HUS/TTP/ITP….