All of the following statements about nateglinide In true except? (AI -2011)
|A||Decreases post-prandial hyperglycemia|
|B||Hypoglycemia is less common than with sulk nylureas|
|C||It decreases insulin resistance|
|D||It acts by releasing insulin|
a. Sulfonylureas, nateglinide and repaglinide act by inhibiting ATP sensitive K channels and thus resulting in release of insulin.
b. Like insulin, all of these drugs can cause hypoglycemia.
c. However, nateglinide therapy produces fewer episodes of hypoglycemia as compared to other oral insulin secretagogue.
d. Nateglinide and repaglinide are short acting and thus can reduce post-prandial hyperglycemia.