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Pathology

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Neoplasia

Question
21 out of 24
 

All of the following genes are most commonly associated with their respective inherited cancer syndromes except: (AIIMS May 2012)



A PTCH – Nevoid Basal cell carcinoma Syndrome

B PTEN – Cowden Syndrome

C LKB-1 – Peutz – Jegher Syndrome

D p 16/ INK4a – Renal cell carcinoma

Ans. D

p16/INK4A gene is associated with melanoma. RCC is associated with VHL gene mutation.

Refer table 7.4 Robbins 8th edition. Page 275

Neoplasia Flashcard List

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