21 out of 24
All of the following genes are most commonly associated with their respective inherited cancer syndromes except: (AIIMS May 2012)
|A||PTCH – Nevoid Basal cell carcinoma Syndrome|
|B||PTEN – Cowden Syndrome|
|C||LKB-1 – Peutz – Jegher Syndrome|
|D||p 16/ INK4a – Renal cell carcinoma|
p16/INK4A gene is associated with melanoma. RCC is associated with VHL gene mutation.
Refer table 7.4 Robbins 8th edition. Page 275