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Medicine

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Liver & GIT

Question
5 out of 9
 

All of the following statements about. Wilson's disease are true, EXCEPT- (AIIMS May 11)



A It is an autosomal recessive disorder

B Serum ceruloplasmin level is reduced

C Urinary copper excretion is reduced

D Zinc acetate is effective as maintenance therapy

Ans. C Urinary copper excretion is reduced

Diagnosis (Ref: Robbins, 7th edition, Pg-911), (H 18th Pg-3188)

1. Increased urinary copper excretion (>100 mcg/24h)

2. Low serum ceruloplasmin levels (<20mcg/dL) (N) 18 – 35 μgm%

3. Themost confirmatory test is elevated hepatic copper concentration (>250 mcg/g of dry liver).

4. Serum copper levels are of no diagnostic value, since they may be low, normal, or elevated, depending on the stage of evolution of the disease.

Liver & GIT Flashcard List

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