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Hematology

Question
19 out of 21
 

All statements about Treatment of Hodgkin's lymphoma are true, Except: (PGI May 2009)



A ABVD is the most commonly used Regimen

B Sterility is more frequent after MOPP than ABVD

C Combination chemotherapy is the mainstay of treatment in Advanced Hodgkin's disease

D WBC count> 15000/mm3 is a poor prognostic factor

Ans. B

Sterility is more frequent after ABVD than MOPP

Treatment of Hodgkin’s disease

1. Stage I (A) and stage II (A)

2. Stage III and stage IV and patient with group B symptoms

Corner stone of treatment is radiotherapy to

involved field

Cornerstone of treatment is combination chemotherapy

Regimen

Agents

Comments

ABVD

(H-18th P-934)

Doxorubicin

Bleomycin

Vinblastine

Dacarbazine

First line treatment of choice

Most popular regimen in United States

More effective than MOPP

Higher incidence of Sterility but less secondary malignancies than MOPP

More satisfactory than MOPP and ABVD in alternating cycles or MOPP/ABV Hybrid

MOPP

Mechlorethamine Vincristine Procarbazine Prednisolone

Less effective and more toxic than ABVD

Lesser incidence of sterility and higher secondary malignancies than

AB VD

Stanford V

Doxorubicin

Bleomycin

Vinblastine

Mechlorethamine

Vincristine

Prednisolone

Etoposide + Radiotherapy

Excellent results but still under investigations / Trail

Hematology Flashcard List

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